G.M. Heilker: search on Z-Library

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1

Confocal Fluorescence Microscopy for High-Throughput Screening of G-Protein Coupled Receptors

Heilker, Ralf, Zemanova, Lenka, Valler, Martin, Nienhaus, G.

Journal:

Current Medicinal Chemistry

Year:

2005

Language:

english

File:

PDF, 294 KB

english, 2005

2

Pharmaceutical Characterization of Tropomyosin Receptor Kinase B-Agonistic Antibodies on Human Induced Pluripotent Stem (hiPS) Cell–Derived Neurons

Traub, Stefanie, Stahl, Heiko, Rosenbrock, Holger, Simon, Eric, Florin, Lore, Hospach, Lisa, Hörer, Stefan, Heilker, Ralf

Journal:

Journal of Pharmacology and Experimental Therapeutics

Year:

2017

Language:

english

File:

PDF, 933 KB

english, 2017

3

The power of combining phenotypic and target-focused drug discovery

Heilker, Ralf, Lessel, Uta, Bischoff, Daniel

Journal:

Drug Discovery Today

Year:

2018

Language:

english

File:

PDF, 597 KB

english, 2018

4

Recognition of sorting signals by clathrin adaptors

Ralf Heilker, Martin Spiess, Pascal Crottet

Journal:

Year:

1999

Language:

english

File:

PDF, 165 KB

english, 1999

5

Clinical pharmacist-initiated asthma management for adult minorities: Does patient education as part of state of the art therapy affect outcomes?

T. Self, T.M. Kelso, N. Abou-Shala, G.M. Heilker, K. Arheart

Journal:

Patient Education and Counseling

Year:

1994

Language:

english

File:

PDF, 72 KB

english, 1994

6

An orally bioavailable positive allosteric modulator of the mGlu4 receptor with efficacy in an animal model of motor dysfunction

Stephen P. East, Samantha Bamford, Matthias G.A. Dietz, Christian Eickmeier, Adam Flegg, Boris Ferger, Mark J. Gemkow, Ralf Heilker, Bastian Hengerer, Adrian Kotey, Pui Loke, Gerhard Schänzle, Hans-Di

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2010

Language:

english

File:

PDF, 616 KB

english, 2010

7

Optimized and Far-Red-Emitting Variants of Fluorescent Protein eqFP611

Simone Kredel, Karin Nienhaus, Franz Oswald, Michael Wolff, Sergey Ivanchenko, Florian Cymer, Andreas Jeromin, Francois J. Michel, Klaus-Dieter Spindler, Ralf Heilker, G. Ulrich Nienhaus, Jörg Wiedenm

Journal:

Chemistry & Biology

Year:

2008

Language:

english

File:

PDF, 872 KB

english, 2008

8

Photoconvertible Fluorescent Protein EosFP: Biophysical Properties and Cell Biology Applications

G. Ulrich Nienhaus, Karin Nienhaus, Angela Hölzle, Sergey Ivanchenko, Fabiana Renzi, Franz Oswald, Michael Wolff, Florian Schmitt, Carlheinz Röcker, Beatrice Vallone, Wolfgang Weidemann, Ralf Heilker,

Journal:

Photochemistry and Photobiology

Year:

2006

Language:

english

File:

PDF, 1.02 MB

english, 2006

9

High-Content Analysis of CCR2 Antagonists on Human Primary Monocytes

Kredel, S., Wolff, M., Hobbie, S., Bieler, M., Gierschik, P., Heilker, R.

Journal:

Journal of Biomolecular Screening

Year:

2011

Language:

english

File:

PDF, 658 KB

english, 2011

10

Novel fluorescent proteins for high-content screening

Michael Wolff, Joerg Wiedenmann, G. Ulrich Nienhaus, Martin Valler, Ralf Heilker

Journal:

Drug Discovery Today

Year:

2006

Language:

english

File:

PDF, 564 KB

english, 2006

11

G-protein-coupled receptor-focused drug discovery using a target class platform approach

Ralf Heilker, Michael Wolff, Christofer S. Tautermann, Michael Bieler

Journal:

Drug Discovery Today

Year:

2009

Language:

english

File:

PDF, 1.56 MB

english, 2009

12

In vivo inhibition of epidermal growth factor receptor autophosphorylation prevents receptor internalization

Michael Wolff, Kay Tetzlaff, Michael C. Nivens, Franz-Josef Schneider, Birgit Jung, Jens Hohlfeld, Ralf Heilker

Journal:

Experimental Cell Research

Year:

2011

Language:

english

File:

PDF, 1.53 MB

english, 2011

13

Confocal optics microscopy for biochemical and cellular high-throughput screening

Lenka Zemanová, Andreas Schenk, Martin J. Valler, G.Ulrich Nienhaus, Ralf Heilker

Journal:

Drug Discovery Today

Year:

2003

Language:

english

File:

PDF, 490 KB

english, 2003

14

All three IκB isoforms and most Rel family members are stably associated with the IκB kinase 1/2 complex

Ralf Heilker, Felix Freuler, Ruth Pulfer, Franco Di Padova, Jörg Eder

Journal:

Year:

1999

Language:

english

File:

PDF, 367 KB

english, 1999

15

CXCR2 Inverse Agonism Detected by Arrestin Redistribution

Kredel, S., Wolff, M., Wiedenmann, J., Moepps, B., Nienhaus, G. U., Gierschik, P., Kistler, B., Heilker, R.

Journal:

Journal of Biomolecular Screening

Year:

2009

Language:

english

File:

PDF, 1023 KB

english, 2009

16

The Kinetics of Association and Phosphorylation of IκB Isoforms by IκB Kinase 2 Correlate with Their Cellular Regulation in Human Endothelial Cells

Heilker, Ralf, Freuler, Felix, Vanek, Miroslava, Pulfer, Ruth, Kobel, Tanja, Peter, Jürg, Zerwes, Hans-Günter, Hofstetter, Hans, Eder, Jörg

Journal:

Year:

1999

Language:

english

File:

PDF, 165 KB

english, 1999

17

Phenotypic Analysis of Chemokine-Driven Actin Reorganization in Primary Human Neutrophils

Kredel, Simone, Wolff, Michael, Gierschik, Peter, Heilker, Ralf

Journal:

Assay and Drug Development Technologies

Year:

2014

Language:

english

File:

PDF, 725 KB

english, 2014

18

Trans−Cis Isomerization is Responsible for the Red-Shifted Fluorescence in Variants of the Red Fluorescent Protein eqFP611

Nienhaus, Karin, Nar, Herbert, Heilker, Ralf, Wiedenmann, Jörg, Nienhaus, G. Ulrich

Journal:

Journal of the American Chemical Society

Year:

2008

Language:

english

File:

PDF, 597 KB

english, 2008

19

iPS cell derived neuronal cells for drug discovery

Heilker, Ralf, Traub, Stefanie, Reinhardt, Peter, Schöler, Hans R., Sterneckert, Jared

Journal:

Trends in Pharmacological Sciences

Year:

2014

Language:

english

File:

PDF, 1.71 MB

english, 2014

20

Assay Related Target Similarity (ARTS) - Chemogenomics Approach for Quantitative Comparison of Biological Targets

Bieler, Michael, Heilker, Ralf, Köppen, Herbert, Schneider, Gisbert

Journal:

Journal of Chemical Information and Modeling

Year:

2011

Language:

english

File:

PDF, 2.52 MB

english, 2011

21

Endothelin Receptor in Virus-Like Particles: Ligand Binding Observed by Fluorescence Fluctuation Spectroscopy †

Zemanová, Lenka, Schenk, Andreas, Hunt, Nicholas, Nienhaus, G. Ulrich, Heilker, Ralf

Journal:

Year:

2004

Language:

english

File:

PDF, 156 KB

english, 2004

22

Public products/public processes: Zoellner's praxis and the contemporary composition classroom

Journal:

Rhetoric Review

Year:

1992

Language:

english

File:

PDF, 418 KB

english, 1992

23

Signal sequence trap: a cloning strategy for secreted proteins and type I membrane proteins

Tashiro, K, Tada, H, Heilker, R, Shirozu, M, Nakano, T, Honjo, T

Journal:

Year:

1993

Language:

english

File:

PDF, 1.18 MB

english, 1993

24

Pharmacological Profiling of Chemokine Receptor-Directed Compounds Using High-Content Screening

Haasen, D., Merk, S., Seither, P., Martyres, D., Hobbie, S., Heilker, R.

Journal:

Journal of Biomolecular Screening

Year:

2007

Language:

english

File:

PDF, 793 KB

english, 2007

25

Possible Nafcillin-Warfarin Interaction

Heilker, Greta M.

Journal:

Archives of Internal Medicine

Year:

1994

Language:

english

File:

PDF, 236 KB

english, 1994

26

Activation and Translocation of Glucokinase in Rat Primary Hepatocytes Monitored by High Content Image Analysis

Wolff, M., Kauschke, S. G., Schmidt, S., Heilker, R.

Journal:

Journal of Biomolecular Screening

Year:

2008

Language:

english

File:

PDF, 965 KB

english, 2008

27

Keywords in Composition Studies

Heilker, Paul, Vandenberg, Peter

Journal:

College Composition and Communication

Year:

1998

Language:

english

File:

PDF, 192 KB

english, 1998

28

Automated High Throughput Screening for Serine Kinase Inhibitors Using a LEADSeekerTM Scintillation Proximity Assay in the 1536-Well Format

Sorg, G., Schubert, H.-D., Buttner, F. H., Heilker, R.

Journal:

Journal of Biomolecular Screening

Year:

2002

Language:

english

File:

PDF, 242 KB

english, 2002

29

Comparison of G-Protein Coupled Receptor Desensitization-Related β- Arrestin Redistribution Using Confocal and Non-Confocal Imaging

Haasen, Dorothea, Wolff, Michael, Valler, Martin, Heilker, Ralf

Journal:

Combinatorial Chemistry & High Throughput Screening

Year:

2006

Language:

english

File:

PDF, 431 KB

english, 2006

30

Automated High Content Screening for Phosphoinositide 3 Kinase Inhibition Using an AKT1 Redistribution Assay

Wolff, Michael, Haasen, Dorothea, Merk, Susanne, Kroner, Margareta, Maier, Udo, Bordel, Sandra, Wiedenmann, Jorg, Nienhaus, Gerd, Valler, Martin, Heilker, Ralf

Journal:

Combinatorial Chemistry & High Throughput Screening

Year:

2006

Language:

english

File:

PDF, 495 KB

english, 2006

31

Adsorption Techniques: Practical Applications || The Mülheim Process for Treating Ruhr River Water

Journal:

American Water Works Association

Year:

1979

Language:

english

File:

PDF, 2.38 MB

english, 1979

32

Literary Theory in the Classroom || "Listener Response": An Introduction to Active Aesthetic Reading for the Sophomore Literature Survey

Journal:

College Literature

Year:

1991

Language:

english

File:

PDF, 745 KB

english, 1991

33

Vibration in Nuclear Heat Exchangers Due to Liquid and Two-Phase Flow

Heilker, W. J., Vincent, R. Q.

Journal:

Journal of Engineering for Power

Year:

1981

Language:

english

File:

PDF, 4.01 MB

english, 1981

34

Comprehensive Long-Term Management Program for Asthma: Effect on Outcomes in Adult African-Americans

Kelso, Tiffany M., Abou-Shala, Nabil, Heilker, Greta M., Arheart, Kristopher L., Portner, Tracy S., Self, Timothy H.

Journal:

The American Journal of the Medical Sciences

Year:

1996

Language:

english

File:

PDF, 6.43 MB

english, 1996

35

High Content Screening of CXCR2-Dependent Signalling Pathways

Wolff, Michael, Krede, Simone, Haasen, Dorothea, Wiedenmann, Jorg, Nienhaus, G., Kistler, Barbara, Oswald, Franz, Heilker, Ralf

Journal:

Combinatorial Chemistry & High Throughput Screening

Year:

2010

Language:

english

File:

PDF, 453 KB

english, 2010

36

Cell-Based Assays in Practice: Cell Markers from Autofluorescent Proteins of the GFP-Family

Wolff, Michael, Kredel, Simone, Wiedenmann, Jorg, Nienhaus, G., Heilker, Ralf

Journal:

Combinatorial Chemistry & High Throughput Screening

Year:

2008

Language:

english

File:

PDF, 336 KB

english, 2008

37

Total System Design || The Mülheim Process

Heinrich Sontheimer, Ewald Heilker, Martin R. Jekel, Heinrich Nolte and Franz H. Vollmer

Journal:

American Water Works Association

Year:

1978

Language:

english

File:

PDF, 1.32 MB

english, 1978

38

A Comment on "Writing beyond the Curriculum"

Journal:

College English

Year:

2001

Language:

english

File:

PDF, 363 KB

english, 2001

39

Public Products/Public Processes: Zoellner's Praxis and the Contemporary Composition Classroom

Journal:

Rhetoric Review

Year:

1992

Language:

english

File:

PDF, 603 KB

english, 1992

40

Upscaling of hiPS Cell–Derived Neurons for High-Throughput Screening

Traub, Stefanie, Stahl, Heiko, Rosenbrock, Holger, Simon, Eric, Heilker, Ralf

Journal:

Journal of Biomolecular Screening

Year:

2016

Language:

english

File:

PDF, 4.53 MB

english, 2016

41

(Research Papers) Time-Resolved Fluorescence Measurements Using Microlens Array and Area Imaging Devices

Merk, Susanne, Lietz, Achim, Kroner, Margareta, Valler, Martin, Heilker, Ralf

Journal:

Combinatorial Chemistry & High Throughput Screening

Year:

2004

Language:

english

File:

PDF, 342 KB

english, 2004

42

Allosteric Activation of Striatal-Enriched Protein Tyrosine Phosphatase (STEP, PTPN5) by a Fragment-like Molecule

Tautermann, Christofer S., Binder, Florian, Büttner, Frank H., Eickmeier, Christian, Fiegen, Dennis, Gross, Ulrike, Grundl, Marc A., Heilker, Ralf, Hobson, Scott, Hoerer, Stefan, Luippold, Andreas, Ma

Journal:

Journal of Medicinal Chemistry

Year:

2018

Language:

english

File:

PDF, 4.01 MB

english, 2018

43

In vitro binding of clathrin adaptors to sorting signals correlates with endocytosis and basolateral sorting.

Heilker, R., Manning-Krieg, U., Zuber, J. F., Spiess, M.

Journal:

The EMBO Journal

Year:

1996

Language:

english

File:

PDF, 1.39 MB

english, 1996

44

The MÃ¼lheim Process

Sontheimer, Heinrich, Heilker, Ewald, Jekel, Martin R., Nolte, Heinrich, Vollmer, Franz H.

Journal:

Journal - American Water Works Association

Year:

1978

File:

PDF, 1.22 MB

1978

45

A small-molecule inhibitor of lectin-like oxidized LDL receptor-1 acts by stabilizing an inactive receptor tetramer state

Schnapp, Gisela, Neubauer, Heike, BÃ¼ttner, Frank H., Handschuh, Sandra, Lingard, Iain, Heilker, Ralf, Klinder, Klaus, Prestle, JÃ¼rgen, Walter, Rainer, Wolff, Michael, Zeeb, Markus, Debaene, Francois

Journal:

Communications Chemistry

Year:

2020

File:

PDF, 3.49 MB

2020

46

Development of a miniaturized 96-Transwell airâliquid interface human small airway epithelial model

Bluhmki, Teresa, Bitzer, Sarah, Gindele, Julia Anna, Schruf, Eva, Kiechle, Tobias, Webster, Megan, Schymeinsky, JÃ¼rgen, Ries, Robert, Gantner, Florian, Bischoff, Daniel, Garnett, James, Heilker, Ralf

Journal:

Scientific Reports

Year:

2020

File:

PDF, 3.24 MB

2020